Article
B cell hyperactivity is a function of T cell derived cytokines in systemic lupus erythematosus.
The Journal of rheumatology - 1 Nov 1993
al-Janadi M, Raziuddin S
Abstract excerpt
OBJECTIVE: T cell abnormalities and abnormal production of cytokines is a key event of B cell hyperactivity and antibody synthesis in systemic lupus erythematosus (SLE). We investigated T cell function and role of interleukin 4 (IL-4) and IL-6 in B cell induced Ig synthesis from SLE. METHODS: Phe...
Topics
- ADP-ribosyl Cyclase
- ADP-ribosyl Cyclase 1
- Adult
- Antigens, CD
- Antigens, Differentiation
- Antigens, Differentiation, B-Lymphocyte
- B-Lymphocytes
- CD4 Antigens
- Cytokines
- Enzyme-Linked Immunosorbent Assay
- Female
- Fluorescent Antibody Technique
- Humans
- Immunoglobulin G
- Integrin beta1
- Interleukin-4
- Interleukin-6
- Leukocyte Common Antigens
