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Article

Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms.

Hepatology (Baltimore, Md.) - 1 Jan 2008

Melum Espen, Karlsen Tom H, Schrumpf Erik, Bergquist Annika, Thorsby Erik, Boberg Kirsten M, Lie Benedicte A

Abstract excerpt

UNLABELLED: Primary sclerosing cholangitis (PSC) is often complicated by the development of cholangiocarcinoma (CCA). Genetic variation of natural killer cell receptor G2D (NKG2D) has been associated with cancer susceptibility. An important ligand for NKG2D, major histocompatibility complex class I chain-related molecule A (MICA), serves as a marker of cellular stress. The 5.1 allele of the gene encoding MICA has...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Cholangitis, Sclerosing

Share to Histocompatibility Antigens Class I

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Source

Identifiers

PMID: 18023027
DOI: 10.1002/hep.21964

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms.PMID 18023027Read ↗

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