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Article

Unique bisphenol A transcriptome in prostate cancer: novel effects on ERbeta expression that correspond to androgen receptor mutation status.

Environmental health perspectives - 1 Nov 2007

Hess-Wilson Janet K, Webb Siobhan L, Daly Hannah K, Leung Yuet-Kin, Boldison Joanne, Comstock Clay E S, Sartor Maureen A, Ho Shuk-Mei, Knudsen Karen E

Abstract excerpt

BACKGROUND: Prostatic adenocarcinomas are dependent on androgen receptor (AR) activity for growth and progression, and therapy for disseminated disease depends on ablation of AR activity. Recurrent tumors ultimately arise wherein AR has been re-activated. One mechanism of AR restoration is via somatic mutation, wherein cells containing mutant receptors become susceptible to activation by alternative ligands,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18007998
DOI: 10.1289/ehp.10283
PMCID: PMC2072856

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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