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<i>In vitro</i> evidence for bisphenol A as a human liver carcinogen: Environmentally relevant doses inhibit cancer-protective ESR1 signaling in a human liver cell line

2025-12-22

Abstract excerpt

I. Several environmentally ubiquitous endocrine disrupting chemicals (EDCs) are suspected carcinogens, but their mechanism(s) of action are unknown. In this study, we test the potential for a model EDC, bisphenol A (BPA), to both initiate (via oxidative mutagenesis) and promote (via endocrine disruption) liver carcinogenesis. This study is motivated by our prior finding that developmental BPA exposure caused hepat...

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Literature Corpus work
dc09bac2-3199-507d-b4c3-8a965180a16a
DOI
10.64898/2025.12.18.695265
Open publication

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<i>In vitro</i> evidence for bisphenol A as a human liver carcinogen: Environmentally relevant doses inhibit cancer-protective ESR1 signaling in a human liver cell lineDOI 10.64898/2025.12.18.695265
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