Article
Investigating the function of the putative mycolic acid methyltransferase UmaA: divergence between the Mycobacterium smegmatis and Mycobacterium tuberculosis proteins.
The Journal of biological chemistry - 18 Jan 2008
Laval Françoise, Haites Ruth, Movahedzadeh Farahnaz, Lemassu Anne, Wong Chinn Yi, Stoker Neil, Billman-Jacobe Helen, Daffé Mamadou
Abstract excerpt
Mycolic acids are major and specific lipid components of the cell envelope of mycobacteria that include the causative agents of tuberculosis and leprosy, Mycobacterium tuberculosis and Mycobacterium leprae, respectively. Subtle structural variations that are known to be crucial for both their virulence and the permeability of their cell envelope occur in mycolic acids. Among these are the introduction of...
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