Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of calcium homeostasis and arrhythmogenesis induced by mutations in the cardiac ryanodine receptor and calsequestrin.

Cardiovascular research - 15 Jan 2008

Liu Nian, Priori Silvia G

Abstract excerpt

Development of cardiac arrhythmias in several degenerative cardiac disorders such as heart failure is precipitated by abnormalities in intracellular calcium regulation. Recently, the identification of mutations in proteins responsible for the control of intracellular calcium has been associated with an inherited arrhythmogenic syndrome called catecholaminergic polymorphic ventricular tachycardia (CPVT). Here, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Calcium
Share to Calsequestrin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Homeostasis

Share to Molecular Sequence Data

Share to Protein Structure, Tertiary

Share to Ryanodine Receptor Calcium Release Channel

Share to Tachycardia, Ventricular

Source

Identifiers

PMID: 18006488
DOI: 10.1093/cvr/cvm004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disruption of calcium homeostasis and arrhythmogenesis induced by mutations in the cardiac ryanodine receptor and calsequestrin.PMID 18006488Read ↗

Inherited dysfunction of sarcoplasmic reticulum Ca2+ handling and arrhythmogenesis.Semantic proximity Read ↗

Molecular and Electrophysiological Bases of Catecholaminergic Polymorphic Ventricular TachycardiaSemantic proximity Read ↗

Molecular and tissue mechanisms of catecholaminergic polymorphic ventricular tachycardia.Semantic proximity Read ↗

Prevention of ventricular arrhythmia and calcium dysregulation in a catecholaminergic polymorphic ventricular tachycardia mouse model carrying calsequestrin-2 mutation.Semantic proximity Read ↗

Ryanodine receptor-mediated arrhythmias and sudden cardiac death.Semantic proximity Read ↗

Sarcoplasmic Reticulum Ca2+ Dysregulation in the Pathophysiology of Inherited Arrhythmia: An Update.Semantic proximity Read ↗

RYR2-ryanodinopathies: from calcium overload to calcium deficiency.Semantic proximity Read ↗

Role of Ca2+ in healthy and pathologic cardiac function: from normal excitation-contraction coupling to mutations that cause inherited arrhythmia.Semantic proximity Read ↗

Calsequestrin mutations and catecholaminergic polymorphic ventricular tachycardia.Semantic proximity Read ↗

Ryanodine receptors and ventricular arrhythmias: emerging trends in mutations, mechanisms and therapies.Semantic proximity Read ↗

Role of ryanodine receptor mutations in cardiac pathology: more questions than answers?Semantic proximity Read ↗

A mutation in calsequestrin, CASQ2D307H, impairs Sarcoplasmic Reticulum Ca2+ handling and causes complex ventricular arrhythmias in miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.