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Article

Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein.

The European journal of neuroscience - 1 Dec 2007

Park Soon S, Schulz Emily M, Lee Daewoo

Abstract excerpt

A key challenge in Parkinson's disease research is to understand mechanisms underlying selective degeneration of dopaminergic neurons mediated by genetic factors such as alpha-synuclein (alpha-Syn). The present study examined whether dopamine (DA)-dependent oxidative stress underlies alpha-Syn-mediated neurodegeneration using Drosophila primary neuronal cultures. Green fluorescent protein (GFP) was used to...

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Identifiers

PMID: 18005066
DOI: 10.1111/j.1460-9568.2007.05929.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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