Article
Cosegregation of CD14 locus and polymorphic alleles of glucocorticoid receptor and protocadherins into CD14 knockout mouse genome.
Shock (Augusta, Ga.) - 1 Jun 2008
Cho Kiho, Hsu Karen, Kwon Deug-Nam, Green Tajia, Lim Debora, Lee Young-Kwan, Greenhalgh David G
Abstract excerpt
Targeted mutagenesis technology has been used to investigate the biological characteristics of genes. We incidentally observed a discrepancy in the size of the glucocorticoid receptor (GCR) between CD14 knockout (KO) mice and backcross controls. The CD14 KO mice were generated using 129S4/SvJae-derived J1 embryonic stem cells, C57BL/ 6J donor blastocysts, and C57BL/6J backcross strain. In this study, the extent...
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