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Article

B cell hyperactivation in an Ackr4-deficient mouse strain is not caused by lack of ACKR4 expression.

Journal of leukocyte biology - 1 Jun 2020

Eckert Nadine, Werth Kathrin, Willenzon Stefanie, Tan Likai, Förster Reinhold

Abstract excerpt

The majority of genetically modified C57BL/6 mice contain congenic passenger DNA around the targeted gene locus as they were generated from 129-derived embryonic stem cells (ESCs) with subsequent backcrossing to the C57BL/6 genetic background. When studying the role of atypical chemokine receptor 4 (ACKR4) in the immune system, we realized that the two available Ackr4-deficient mouse strains (Ackr4-/- and...

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Identifiers

PMID: 31841228
DOI: 10.1002/JLB.2MA1119-300R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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