Article
Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the United States of America - 20 Nov 2007
Hartung Frank, Suer Stefanie, Puchta Holger
Abstract excerpt
RecQ helicases are involved in the processing of DNA structures arising during replication, recombination, and repair throughout all kingdoms of life. Mutations of different RecQ homologues are responsible for severe human diseases, such as Blooms (BLM) or Werner (WRN) syndrome. The loss of RecQ function is often accompanied by hyperrecombination caused by a lack of crossover suppression. In the Arabidopsis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.