Allelic variant in CTLA4 alters T cell phosphorylation patterns.

doi:10.1073/pnas.0706409104

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Article

Allelic variant in CTLA4 alters T cell phosphorylation patterns.

Proceedings of the National Academy of Sciences of the United States of America - 20 Nov 2007

Maier Lisa M, Anderson David E, De Jager Philip L, Wicker Linda S, Hafler David A

Abstract excerpt

Little is known regarding the functional effects of common autoimmune susceptibility variants on human immune cells. The SNP CT60 (rs3087243; A/G) located in the 3' UTR of the CTLA4 gene has been associated with autoimmune diseases. We examined a cohort of healthy individuals stratified by genotypes at CTLA4 to gain insight into the functional effects of allelic variation on T cell signaling. Using...

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Identifiers

PMID: 18000051
DOI: 10.1073/pnas.0706409104
PMCID: PMC2141824

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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