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Article

CTLA4 +49 A/G and CT60 polymorphisms in Dutch coeliac disease patients.

European journal of human genetics : EJHG - 1 Sept 2004

van Belzen Martine J, Mulder Chris J J, Zhernakova Alexandra, Pearson Peter L, Houwen Roderick H J, Wijmenga Cisca

Abstract excerpt

Coeliac disease is an autoimmune disorder, characterised by villous atrophy of the small intestine, which results from a T-cell-mediated response to gluten-derived peptides. The cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is involved in the regulation of T-cell activation and the CTLA4 +49 A/G polymorphism in exon 1 has been implicated in several autoimmune disorders, including coeliac disease. However,...

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Source

Identifiers

PMID: 15199380
DOI: 10.1038/sj.ejhg.5201165

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CTLA4 +49 A/G and CT60 polymorphisms in Dutch coeliac disease patients.PMID 15199380Read ↗

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