Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of islet-like hormone-producing cells in vitro from adult human pancreas.

Cell transplantation - 1 Jan 2005

Atouf Fouad, Choi Yong, Fowler Michael J, Poffenberger Greg, Vobecky Jan, Ta Malancha, Chapman George B, Powers Alvin C, Lumelsky Nadya L

Abstract excerpt

Transplantation of pancreatic islets can provide long-lasting insulin independence for diabetic patients, but the current islet supply is limited. Here we describe a new in vitro system that utilizes adult human pancreatic islet-enriched fractions to generate hormone-producing cells over 3-4 weeks of culture. By labeling proliferating cells with a retrovirus-expressing green fluorescent protein, we show that in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to C-Peptide
Share to Cell Culture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose

Share to Insulin Secretion

Share to Islets of Langerhans

Share to Islets of Langerhans Transplantation

Share to Mice, Inbred NOD

Share to Mice, SCID

Source

Identifiers

PMID: 16454348
DOI: 10.3727/000000005783982602

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of islet-like hormone-producing cells in vitro from adult human pancreas.PMID 16454348Read ↗

Generation and long-term expansion of human pancreatic islet organoids <i>in vitro</i>Semantic proximity Read ↗

Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor CellsSemantic proximity Read ↗

Three-Dimensional Differentiation of Embryonic Stem Cells into Islet-like Insulin-Producing ClustersSemantic proximity Read ↗

Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cellsSemantic proximity Read ↗

Generation of Insulin-Producing Islet-Like Clusters from Human Embryonic Stem CellsSemantic proximity Read ↗

Pancreatic islet cell development and regenerationSemantic proximity Read ↗

Adult pancreas generates multipotent stem cells and pancreatic and nonpancreatic progeny.Semantic proximity Read ↗

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretionSemantic proximity Read ↗

A perfect islet: reviewing recent protocol developments and proposing strategies for stem cell derived functional pancreatic isletsSemantic proximity Read ↗

Islet organoid as a promising model for diabetesSemantic proximity Read ↗

The adult mouse and human pancreas contain rare multipotent stem cells that express insulin.Semantic proximity Read ↗

Expansion and Differentiation of Adult Human Pancreas-Derived Progenitor Cells into Functional Islet-Like OrganoidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.