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Article

Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor.

Circulation - 27 Nov 2007

Stroud Dina Myers, Gaussin Vinciane, Burch John B E, Yu Cindy, Mishina Yuji, Schneider Michael D, Fishman Glenn I, Morley Gregory E

Abstract excerpt

BACKGROUND: The atrioventricular (AV) node is essential for the sequential excitation and optimized contraction of the adult multichambered heart; however, relatively little is known about its formation from the embryonic AV canal. A recent study demonstrated that signaling by Alk3, the type 1a receptor for bone morphogenetic proteins, in the myocardium of the AV canal was required for the development of both the...

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Identifiers

PMID: 17998461
DOI: 10.1161/CIRCULATIONAHA.107.696583
PMCID: PMC2947829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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