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Article

Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice.

The Journal of experimental medicine - 26 Nov 2007

Roy Marie-France, Riendeau Noémie, Bédard Christian, Hélie Pierre, Min-Oo Gundula, Turcotte Karine, Gros Philippe, Canonne-Hergaux François, Malo Danielle

Abstract excerpt

The mouse response to acute Salmonella typhimurium infection is complex, and it is under the influence of several genes, as well as environmental factors. In a previous study, we identified two novel Salmonella susceptibility loci, Ity4 and Ity5, in a (AcB61 x 129S6)F2 cross. The peak logarithm of odds score associated with Ity4 maps to the region of the liver and red blood cell (RBC)-specific pyruvate kinase...

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Identifiers

PMID: 17998386
DOI: 10.1084/jem.20062606
PMCID: PMC2118530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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