Article
[Molecular genetics of autoimmune diabetes].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2010
Zha Min, Yang Tao, Chen Jia-wei
Abstract excerpt
Autoimmune diabetes is a T cell-mediated disease characterized by the autoimmune destruction of pancreatic β-cells and insulin deficiency. It is related to multiple genes. The IDDM1 locus, which lies within the human leukocyte antigen (HLA) and the IDDM2 locus, which is located to the insulin gene region, are two major genetic contributors of susceptibility. Many other loci conferring susceptibility to autoimmune...
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