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Article

Mouse Sertoli cells display phenotypical and functional traits of antigen-presenting cells in response to interferon gamma.

Biology of reproduction - 1 Feb 2008

Dal Secco Valentina, Riccioli Anna, Padula Fabrizio, Ziparo Elio, Filippini Antonio

Abstract excerpt

The testis is regarded as an immunologically privileged site because it tolerates either autoantigenic germ cells or allografts. Because the blood testis barrier represents an incomplete immunological barrier, we have explored whether Sertoli cells, the somatic cells of the seminiferous epithelium, might play an active role in immune evasion. We report data indicating that B7-H1(officially known as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17989360
DOI: 10.1095/biolreprod.107.063578

Genes

IFNG
FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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