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CD28 co-stimulation in T-cell homeostasis: a recent perspective

1 May 2015

Abstract excerpt

T-cells play a key role within the adaptive immune system mediating cellular immunity and orchestrating the immune response as a whole. Their activation requires not only recognition of antigen/major histocompatibility complexes by the T-cell receptor but in addition co-stimulation via the CD28 molecule through binding to CD80, CD86, or as recently discovered, inducible co-stimulator ligand expressed by...

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PMID: 27471717
DOI: 10.2147/itt.s61647

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