Article
Prion protein M129V polymorphism affects retrieval-related brain activity.
Neuropsychologia - 1 Jan 2008
Buchmann Andreas, Mondadori Christian R A, Hänggi Jürgen, Aerni Amanda, Vrticka Pascal, Luechinger Roger, Boesiger Peter, Hock Christoph, Nitsch Roger M, de Quervain Dominique J-F, Papassotiropoulos Andreas, Henke Katharina
Abstract excerpt
The prion protein Met129Val polymorphism has recently been related to human long-term memory with carriers of either the 129MM or the 129MV genotype recalling 17% more words than 129(VV) carriers at 24h following learning. Here, we sampled genotype differences in retrieval-related brain activity at 30min and 24h following learning. Furthermore, genotype groups were compared regarding grey matter concentrations...
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