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Article

PAI and TPA gene polymorphisms in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Mar 2008

Lovrecic Luca, Ristić Smiljana, Starcević-Cizmarević Nada, Brajenović-Milić Bojana, Jazbec Sasa Sega, Sepcić Juraj, Kapović Miljenko, Peterlin Borut

Abstract excerpt

Multiple sclerosis (MS) is an immune-mediated chronic inflammatory demyelinating disease of the central nervous system. It manifests as acute focal inflammatory demyelination and axonal loss with limited remyelination and results in the chronic multifocal sclerotic plaques. Previously published data showed impaired fibrinolysis in MS. Tissue plasminogen activator t-PA is a serine protease that catalyses the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17986506
DOI: 10.1177/1352458507082603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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