Article
Genetic determinants of arterial thrombosis.
Bailliere's clinical haematology - 1 Sept 1994
Green F, Humphries S
Abstract excerpt
This chapter describes examples of genetic variation determining plasma levels of three independent risk factors for arterial thrombotic disease, namely fibrinogen, coagulation factor VII and plasminogen activator inhibitor type 1, together with a discussion of the underlying molecular mechanisms. In each case, the data suggest that there is interaction between genotype and environment in determination of the...
Topics
- Afibrinogenemia
- Arteries
- Environment
- Factor VII
- Factor VII Deficiency
- Fibrinogens, Abnormal
- Genetic Predisposition to Disease
- Humans
- Hypertriglyceridemia
- Interleukin-1
- Myocardial Infarction
- Plasminogen Activator Inhibitor 1