Article
Genetic determinants of arterial thrombosis.
Bailliere's best practice & research. Clinical haematology - 1 Sept 1999
Grant P J, Humphries S E
Abstract excerpt
This chapter describes examples of genetic variation involved in the function or regulation of a number of haemostatic proteins involved in the thrombotic process. In each case, the data suggest associations between genotype and disease and, particularly in the case of fibrinogen, PAI-1, Factor VII and Factor XIII, there is interaction between genotype and environment in determination of the relevant plasma...
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