Article
Detection of single-nucleotide polymorphisms in cancer-related genes by minisequencing on a microelectronic DNA chip.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Ho-Pun-Cheung Alexandre, Abaibou Hafid, Cleuziat Philippe, Lopez-Crapez Evelyne
Abstract excerpt
The ability to realize simultaneous genotyping of multiple single-nucleotide polymorphisms or mutations is valuable in DNA samples from complex multigenic pathologies such as cancer. In this way, the complexity (number of hybridization units per chip) of the developed MICAM DNA chip, and the orientation of the grafted pyrrole oligonucleotides, make it particularly well adapted to the analysis of single-nucleotide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
