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Article

Biochip-Based Genotyping Assay for Detection of Polymorphisms in Pigmentation Genes Associated with Cutaneous Melanoma.

Genetic testing and molecular biomarkers - 1 Apr 2016

Fesenko Denis O, Chudinov Alexander V, Surzhikov Sergey A, Zasedatelev Alexander S

Abstract excerpt

AIMS: The purpose of the study was to develop a new assay for genotyping nine single nucleotide polymorphisms (SNPs) that are known to be associated with melanoma. METHODS: Two-stage single tube polymerase chain reaction (PCR) followed by hybridization on a biochip was developed and applied in the study. RESULTS: A total of nine SNPs were selected from five genes: MC1R (rs1805006, rs1805007, rs1805009,...

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Topics

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Share to Genotyping Techniques
Share to Melanoma
Share to Melanoma, Cutaneous Malignant
Share to Membrane Transport Proteins
Share to Microarray Analysis
Share to Nucleic Acid Hybridization
Share to Pigmentation
Share to Skin Neoplasms

Source

Identifiers

PMID: 26848990
DOI: 10.1089/gtmb.2015.0272

Genes

HERC2
OCA2
TYR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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