Article
Apolipoprotein E genotype and lipid and lipoprotein levels in dementia.
Dementia and geriatric cognitive disorders - 1 Jan 2000
Wehr H, Parnowski T, Puzyński S, Bednarska-Makaruk M, Bisko M, Kotapka-Minc S, Rodo M, Wołkowska M
Abstract excerpt
In 64 individuals with dementia (26 Alzheimer type, 34 of vascular origin and 4 other types of dementia) apolipoprotein E genotype was identified. Frequency of epsilon4 allele was 36.5% in Alzheimer patients and 32.4% in vascular dementia ones. In a group of 39 nondemented individuals of the same age the epsilon4 frequency was 11.5%. In demented patients, carriers of epsilon4, a tendency to higher plasma levels...
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