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Article

Expression of Histamine H4 Receptor in Synovial Cells from Rheumatoid Arthritic Patients

1 Jan 2007

Abstract excerpt

The last of four histamine receptors (HRs), H4 receptor (H4R), was identified in the year 2000. Since that time, the H4R has been implicated in cellular mechanisms related to immune systems, inflammatory processes, and allergic reactions. We have previously reported the expression of H4R mRNA in rheumatoid arthritic (RA) synovial cell cultures by means of the RT-PCR method. The present study demonstrates the...

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PMID: 17978505
DOI: 10.1248/bpb.30.2217

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