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Article

Accurate prediction of enzyme mutant activity based on a multibody statistical potential.

Bioinformatics (Oxford, England) - 1 Dec 2007

Masso Majid, Vaisman Iosif I

Abstract excerpt

MOTIVATION: An important area of research in biochemistry and molecular biology focuses on characterization of enzyme mutants. However, synthesis and analysis of experimental mutants is time consuming and expensive. We describe a machine-learning approach for inferring the activity levels of all unexplored single point mutants of an enzyme, based on a training set of such mutants with experimentally measured...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17977887
DOI: 10.1093/bioinformatics/btm509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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