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Article

A Data-Driven Evolutionary Algorithm for Mapping Multibasin Protein Energy Landscapes.

Journal of computational biology : a journal of computational molecular cell biology - 1 Sept 2015

Clausen Rudy, Shehu Amarda

Abstract excerpt

Evidence is emerging that many proteins involved in proteinopathies are dynamic molecules switching between stable and semistable structures to modulate their function. A detailed understanding of the relationship between structure and function in such molecules demands a comprehensive characterization of their conformation space. Currently, only stochastic optimization methods are capable of exploring...

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PMID: 26203626
DOI: 10.1089/cmb.2015.0107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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