Article
Four-body scoring function for mutagenesis.
Bioinformatics (Oxford, England) - 15 Nov 2007
Deutsch Chris, Krishnamoorthy Bala
Abstract excerpt
MOTIVATION: There is a need for an efficient and accurate computational method to identify the effects of single- and multiple-residue mutations on the stability and reactivity of proteins. Such a method should ideally be consistent and yet applicable in a widespread manner, i.e. it should be applied to various proteins under the same parameter settings, and have good predictive power for all of them. RESULTS: We...
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