Article
Netrin-G2 and netrin-G2 ligand are both required for normal auditory responsiveness.
Genes, brain, and behavior - 1 Jun 2008
Zhang W, Rajan I, Savelieva K V, Wang C-Y, Vogel P, Kelly M, Xu N, Hasson B, Jarman W, Lanthorn T H
Abstract excerpt
Mice in which netrin-G2 has been genetically inhibited do not startle to an acoustic stimulus, but otherwise perform normally through a behavioral test battery. Light microscopic examination of the inner ear showed no obvious structural abnormalities. Brainstem responses to acoustic stimuli (auditory brainstem responses, ABR) were also present, confirming the lack of any overarching defects in the inner ear or...
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