Article
Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior.
Proceedings of the National Academy of Sciences of the United States of America - 21 Nov 2000
Contos J J, Fukushima N, Weiner J A, Kaushal D, Chun J
Abstract excerpt
Although extracellular application of lysophosphatidic acid (LPA) has been extensively documented to produce a variety of cellular responses through a family of specific G protein-coupled receptors, the in vivo organismal role of LPA signaling remains largely unknown. The first identified LPA receptor gene, lp(A1)/vzg-1/edg-2, was previously shown to have remarkably enriched embryonic expression in the cerebral...
Topics
- Animals
- Animals, Newborn
- Animals, Suckling
- Cerebral Cortex
- Craniofacial Abnormalities
- Crosses, Genetic
- Female
- Fetal Death
- Gene Deletion
- Genotype
- Growth Disorders
- Lysophospholipids
- Male
- Mice