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Article

The basal-like breast carcinoma phenotype is regulated by SLUG gene expression.

The Journal of pathology - 1 Jan 2008

Storci G, Sansone P, Trere D, Tavolari S, Taffurelli M, Ceccarelli C, Guarnieri T, Paterini P, Pariali M, Montanaro L, Santini D, Chieco P, Bonafé M

Abstract excerpt

Basal-like breast carcinoma is an aggressive form of breast cancer, characterized by the absence of oestrogen receptor and HER2 expression, the presence of cytokeratin 5 and epidermal growth factor receptor expression, and by the up-regulation of stem cell regulatory genes. We show here that tumo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17973239
DOI: 10.1002/path.2254

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17973239-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The basal-like breast carcinoma phenotype is regulated by SLUG gene expression.PMID 17973239Read ↗

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SLUG: Critical regulator of epithelial cell identity in breast development and cancerSemantic proximity Read ↗

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Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate.Semantic proximity Read ↗

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BRCA1 regulates human mammary stem/progenitor cell fateSemantic proximity Read ↗

Slug/β-catenin-dependent proinflammatory phenotype in hypoxic breast cancer stem cells.Semantic proximity Read ↗

Distinct patterns of promoter CpG island methylation of breast cancer subtypes are associated with stem cell phenotypes.Semantic proximity Read ↗

High expression of stem cell marker ALDH1 is associated with reduced BRCA1 in invasive breast carcinomas.Semantic proximity Read ↗

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