Article
Paclitaxel resistance in untransformed human mammary epithelial cells is associated with an aneuploidy-prone phenotype.
British journal of cancer - 5 Nov 2007
Bouchet B P, Bertholon J, Falette N, Audoynaud C, Lamblot C, Puisieux A, Galmarini C M
Abstract excerpt
Despite its increasing clinical use, almost no data are currently available about paclitaxel effects on non-cancerous mammary epithelial cells. We have previously established paclitaxel-resistant sub-cell lines (paclitaxel-surviving populations, PSPs; n=20), and sensitive controls (control clones, CCs; n=10), from the untransformed human mammary epithelial cell line HME1. In this study, we aimed to establish...
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