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Heat Shock Transcription Factor 1 Is Required for Maintenance of Ciliary Beating in Mice

27 Oct 2007

Abstract excerpt

Heat shock transcription factors (HSFs) maintain protein homeostasis through regulating expression of heat shock proteins, especially in stressed conditions. In addition, HSFs are involved in cellular differentiation and development by regulating development-related genes, as well as heat shock genes. Here, we showed chronic sinusitis and mild hydrocephalus in postnatal HSF1-null mice, which are associated with...

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PMID: 17965413
DOI: 10.1074/jbc.m704562200

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