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Article

Small heat shock proteins Hspb7 and Hspb12 regulate early steps of cardiac morphogenesis.

Developmental biology - 15 Sept 2013

Rosenfeld Gabriel E, Mercer Emily J, Mason Christopher E, Evans Todd

Abstract excerpt

Cardiac morphogenesis is a complex multi-stage process, and the molecular basis for controlling distinct steps remains poorly understood. Because gata4 encodes a key transcriptional regulator of morphogenesis, we profiled transcript changes in cardiomyocytes when Gata4 protein is depleted from developing zebrafish embryos. We discovered that gata4 regulates expression of two small heat shock genes, hspb7 and...

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Identifiers

PMID: 23850773
DOI: 10.1016/j.ydbio.2013.06.025
PMCID: PMC3777613

Genes

HSPB7
GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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