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Article

Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation.

Genesis (New York, N.Y. : 2000) - 1 Dec 2004

Min Jin-Na, Zhang Yan, Moskophidis Demetrius, Mivechi Nahid F

Abstract excerpt

Mammalian ocular lens development results via a differentiation program that is highly regulated by tissue-specific transcription factors. Central to this is the terminal differentiation of fiber cells, which develop from epithelial cells on the anterior surface of the lens, accompanied by a change in cell shape and expression of structural proteins (such as membrane proteins MP19, MIP26, connexin 43, 46, and 50,...

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Share to Cell Differentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

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Share to Heat Shock Transcription Factors

Share to Lens, Crystalline

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Source

Identifiers

PMID: 15593327
DOI: 10.1002/gene.20087

Genes

HSF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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