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Article

Heat shock factor 1 is required for constitutive Hsp70 expression and normal lens development in embryonic zebrafish.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology - 1 Jan 2007

Evans Tyler G, Belak Zachery, Ovsenek Nick, Krone Patrick H

Abstract excerpt

Heat shock factors (HSFs) are the major transcription factors responsible for heat-induced upregulation of heat shock protein (Hsp) genes. All three mammalian HSFs (HSF1, HSF2, HSF4) have also been shown to be required for normal mammalian development. It is currently unknown if HSFs play similarly important roles during normal development of non-mammalian vertebrates. In the present study, a morpholino modified...

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Share to Electrophoretic Mobility Shift Assay
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to HSP70 Heat-Shock Proteins

Share to Lens, Crystalline

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Share to Oligodeoxyribonucleotides, Antisense

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Source

Identifiers

PMID: 17134927
DOI: 10.1016/j.cbpa.2006.09.023

Genes

HSF1
HSF2
HSF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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