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Article

The metalloprotease of Listeria monocytogenes is activated by intramolecular autocatalysis.

Journal of bacteriology - 1 Jan 2008

Bitar Alan Pavinski, Cao Min, Marquis Hélène

Abstract excerpt

The metalloprotease (Mpl) of Listeria monocytogenes is a thermolysin-like protease that mediates the maturation of a broad-range phospholipase C, whose function contributes to the ability of this food-borne bacterial pathogen to survive intracellularly. Mpl is made as a proprotein that undergoes maturation by proteolytic cleavage of a large N-terminal prodomain. In this study, we identified the N terminus of...

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Identifiers

PMID: 17965168
DOI: 10.1128/JB.00852-07
PMCID: PMC2223762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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