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Article

A new TetR family transcriptional regulator required for morphogenesis in Streptomyces coelicolor.

Journal of bacteriology - 1 Jan 2008

Hillerich Brandan, Westpheling Janet

Abstract excerpt

Both morphogenesis and antibiotic production in the streptomycetes are initiated in response to starvation, and these events are coupled. We previously described a transposon-generated mutant in Streptomyces coelicolor, SE293, that resulted in a bld strain that overproduced the antibiotic actinorhodin. The SCO1135 open reading frame identified by the insertion encodes a member of the TetR family of...

Topics

Bacterial Proteins
DNA Primers
Escherichia coli
Microscopy, Electron, Scanning
Morphogenesis
Mutagenesis
Phenotype
RNA, Bacterial
Reverse Transcriptase Polymerase Chain Reaction
Sequence Deletion
Streptomyces coelicolor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Transcription, Genetic

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Identifiers

PMID: 17965158
DOI: 10.1128/JB.01316-07
PMCID: PMC2223726

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