Article
A new TetR family transcriptional regulator required for morphogenesis in Streptomyces coelicolor.
Journal of bacteriology - 1 Jan 2008
Hillerich Brandan, Westpheling Janet
Abstract excerpt
Both morphogenesis and antibiotic production in the streptomycetes are initiated in response to starvation, and these events are coupled. We previously described a transposon-generated mutant in Streptomyces coelicolor, SE293, that resulted in a bld strain that overproduced the antibiotic actinorhodin. The SCO1135 open reading frame identified by the insertion encodes a member of the TetR family of...
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