Article
SarA influences the sporulation and secondary metabolism in Streptomyces coelicolor M145.
Acta biochimica et biophysica Sinica - 1 Oct 2008
Ou Xijun, Zhang Bo, Zhang Lin, Dong Kai, Liu Chun, Zhao Guoping, Ding Xiaoming
Abstract excerpt
The filamentous bacteria Streptomyces exhibit a complex life cycle involving morphological differentiation and secondary metabolism. A putative membrane protein gene sarA (sco4069), sporulation and antibiotic production related gene A, was partially characterized in Streptomyces coelicolor M145. The gene product had no characterized functional domains and was highly conserved in Streptomyces. Compared with the...
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