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Article

Association between CFH Y402H polymorphism and age related macular degeneration in North Indian cohort.

PloS one - 1 Jan 2013

Sharma Neel Kamal, Gupta Amod, Prabhakar Sudesh, Singh Ramandeep, Sharma Suresh Kumar, Chen Wei, Anand Akshay

Abstract excerpt

The purpose of the study was to determine serum complement factor H (CFH) levels in patients of age related macular degeneration (AMD) and examine its association with CFH Y402H polymorphism. 115 AMD patients and 61 normal controls were recruited in this study. The single nucleotide polymorphism was assayed by real time PCR and serum CFH levels were measured by ELISA and standardized to total serum protein....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23922956
DOI: 10.1371/journal.pone.0070193
PMCID: PMC3726372

Genes

CFH

Variants

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