Article
Imaging of amyloid plaques and cerebral glucose metabolism in semantic dementia and Alzheimer's disease.
NeuroImage - 15 Jan 2008
Drzezga Alexander, Grimmer Timo, Henriksen Gjermund, Stangier Isabelle, Perneczky Robert, Diehl-Schmid Janine, Mathis Chester A, Klunk William E, Price Julie, DeKosky Steve, Wester Hans-Jürgen, Schwaiger Markus, Kurz Alexander
Abstract excerpt
Semantic dementia (SD) is a rare clinical syndrome, assigned to the group of frontotemporal lobar degenerations (FTLD). Histopathological analysis has not revealed the deposition of amyloid plaques in the majority of SD cases, in contrast to dementia of the Alzheimer type (AD). However, based on clinical examination alone a reliable differentiation of the underlying pathology cannot be guaranteed, i.e. AD and SD...
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