Article
Association between FDG uptake, CSF biomarkers and cognitive performance in patients with probable Alzheimer's disease.
European journal of nuclear medicine and molecular imaging - 1 Jul 2009
Arlt Sönke, Brassen Stefanie, Jahn Holger, Wilke Florian, Eichenlaub Martin, Apostolova Ivayla, Wenzel Fabian, Thiele Frank, Young Stewart, Buchert Ralph
Abstract excerpt
PURPOSE: Brain imaging of FDG uptake and cerebrospinal fluid (CSF) concentration of amyloid-beta 1-42 (Abeta(1-42)) or tau proteins are promising biomarkers in the diagnosis of Alzheimer's disease (AD). There is still uncertainty regarding any association between decreased FDG uptake and alterations in CSF markers. METHODS: The relationship between FDG uptake, CSF Abeta(1-42) and total tau (T-tau), as well as the...
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