Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Search for quantitative trait loci of atopy-associated immune responses using allergen-specific IgG1 as an "endophenotype".

Human immunology - 1 Oct 2007

Jackola Duaine R, Miller Michael B, Liebeler Carol L, Blumenthal Malcolm N

Abstract excerpt

Inherited atopic diseases of humans arise from adverse adaptive humoral responses to noninfectious environmental allergens. We previously reported that allergen-specific IgG1 provides more reliable heritability estimates for responses to allergens than total IgE. Genome scans were done for 91 Caucasian nuclear families with history of atopy for total IgE and IgG1 produced against a common major allergen from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Dermatophagoides
Share to Arthropod Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asthma

Share to Cysteine Endopeptidases

Share to Hypersensitivity, Immediate

Share to Immunoglobulin E

Share to Immunoglobulin G

Share to Skin Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 17961772
DOI: 10.1016/j.humimm.2007.07.006
PMCID: PMC2083299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Search for quantitative trait loci of atopy-associated immune responses using allergen-specific IgG1 as an "endophenotype".PMID 17961772Read ↗

Allergen-specific IgG1 provides parsimonious heritability estimates for atopy-associated immune responses to allergens.Semantic proximity Read ↗

Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus.Semantic proximity Read ↗

Current concepts of IgE regulation and impact of genetic determinantsSemantic proximity Read ↗

Fine-mapping of IgE-associated loci 1q23, 5q31, and 12q13 using 1000 Genomes Project data.Semantic proximity Read ↗

Analysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk.Semantic proximity Read ↗

Genome-wide association studies on IgE regulation: are genetics of IgE also genetics of atopic disease?Semantic proximity Read ↗

Transcriptome-wide Association Study of Circulating IgE Levels Identifies Novel Targets for Asthma and Allergic DiseasesSemantic proximity Read ↗

The genome-wide association study of serum IgE levels demonstrated a shared genetic background in allergic diseases.Semantic proximity Read ↗

A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study.Semantic proximity Read ↗

Genetic variability of the high-affinity IgE receptor alpha subunit (Fc epsilon RI alpha) is related to total serum IgE levels in allergic subjects.Semantic proximity Read ↗

A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom.Semantic proximity Read ↗

Different FCER1A polymorphisms influence IgE levels in asthmatics and non-asthmatics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.