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Article

Regulation of collagen gene expression in the Tsk2 mouse.

Journal of cellular physiology - 1 May 2008

Barisic-Dujmovic Tatjana, Boban Ivana, Clark Stephen H

Abstract excerpt

The tight skin 2 (Tsk2) mutation is an ENU induced dominant mutation localized on mouse chromosome 1. While the molecular defect is unknown, Tsk2/+ mice display cutaneous thickening associated with excessive matrix production and are used as a model of scleroderma. The purpose of this study was to examine the cellular mechanisms associated with the excessive synthesis of matrix macromolecules using a collagen...

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Source

Identifiers

PMID: 17960558
DOI: 10.1002/jcp.21319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulation of collagen gene expression in the Tsk2 mouse.PMID 17960558Read ↗

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