Article
Cooperating mutations of receptor tyrosine kinases and Ras genes in childhood core-binding factor acute myeloid leukemia and a comparative analysis on paired diagnosis and relapse samples.
Leukemia - 1 Feb 2008
Shih L-Y, Liang D-C, Huang C-F, Chang Y-T, Lai C-L, Lin T-H, Yang C-P, Hung I-J, Liu H-C, Jaing T-H, Wang L-Y, Yeh T-C
Abstract excerpt
c-KIT mutations have been described in core-binding factor (CBF) acute myeloid leukemia (AML) at diagnosis. The role of c-KIT mutations in the relapse of CBF-AML is not clear. The role of CSF1R mutation in the pathogenesis of AML remains to be determined. We analyzed receptor tyrosine kinases (RT...
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