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KIT and FLT3-ITD Mutations Do Not Predict Outcomes in Pediatric Core-Binding Factor Acute Myeloid Leukemia: Findings from the C-HUANAN-AML-15 Multicenter Cohort Study

2026-01-12

Abstract excerpt

<title>Abstract</title> <p> Background Although core-binding factor acute myeloid leukemia (CBF-AML) is generally considered a favorable-risk subtype in children, disease relapse remains a significant concern. The prognostic relevance of co-occurring mutations, particularly <italic>KIT</italic> and <italic>FLT3-ITD</italic> , remains debatable, and treatment intensity may modulate their impact. Methods Thi...

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Literature Corpus work
6ff68429-dbb8-5f79-86b0-ef435a01a24c
DOI
10.21203/rs.3.rs-8473547/v1
Open publication

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KIT and FLT3-ITD Mutations Do Not Predict Outcomes in Pediatric Core-Binding Factor Acute Myeloid Leukemia: Findings from the C-HUANAN-AML-15 Multicenter Cohort StudyDOI 10.21203/rs.3.rs-8473547/v1
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