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Article

Apoptosis is involved in the senescence of endothelial cells induced by angiotensin II

26 Oct 2007

Abstract excerpt

Vascular endothelial cells have a finite cell lifespan and eventually enter an irreversible growth arrest, cellular senescence. The functional changes associated with cellular senescence are thought to contribute to human aging and age-related cardiovascular disorders, e.g. atherosclerosis. In this study, induction of Angiotensin II (Ang II) promoted a growth arrest with phenotypic characteristics of cell...

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PMID: 17959395
DOI: 10.1016/j.cellbi.2007.09.003

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