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Article

Vascular endothelial senescence: from mechanisms to pathophysiology

26 Nov 2008

Abstract excerpt

Most mitotically competent mammalian cell types can react to stress by undergoing a phenotypically distinctive and permanent form of growth arrest called "cellular senescence." This response has been extensively characterized in cell culture and more recently it has been found to occur also in vivo in a number of tissues. In this review I will present the case for the occurrence of senescence in the vascular...

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PMID: 19036896
DOI: 10.1152/japplphysiol.91353.2008

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