Article
Endothelial cell senescence.
Handbook of experimental pharmacology - 1 Jan 2006
Erusalimsky J D, Kurz D J
Abstract excerpt
The wear and tear processes that are thought to contribute to human ageing may play an important role in the development of vascular diseases. One such process is cellular senescence. In endothelial cells the senescent phenotype can be induced by a number of factors, including telomere damage, oxidative stress and sustained mitogenic stimulation. Several lines of evidence indicate that endothelial cell senescence...
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